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In-Service Exam
Cleft Lip/Palate - 2003






During embryologic development, which of the following structures arises from the frontonasal processes?

(A) Columella
(B) Nasal bridge
(C) Nasal septum
(D) Nasal tip
(E) Philtrum

Reproduced with permission of Arey LB, ed. Developmental Anatomy. 26th ed. Philadelphia, Pa: WB Saunders Co; 1970.


The correct response is Option B.

During embryologic development, the nasal structures form during the sixth week of gestation as the frontonasal and medial nasal processes enlarge and coalesce in the midline. Any abnormalities occurring during this gestational stage are likely to lead to the development of a cleft nasal deformity or other nasal deformities.
References
1. Arey LB, ed. Developmental Anatomy. 26th ed. Philadelphia, Pa: WB Saunders Co; 1970.
2. Gosain AK, Moore FO. Embryology of the head and neck. In: Aston SJ, Beasley RW, Thorne CH, eds. Grabb & Smith's Plastic Surgery. 5th ed. Philadelphia, Pa: Lippincott-Raven; 1997:223-236.
3. Johnston MC, Bronsky PT, Millicovsky G. Embryogenesis of cleft lip and palate. In: McCarthy JG, ed. Plastic Surgery. Philadelphia, Pa: WB Saunders Co; 1990;4:2525.


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